CeNTI -

The European project INTEGRANO aims to develop an integrated, evidence-based approach for the design of safe and sustainable Nanomaterials (NMs) and Nano-enabled Products (NEPs), aligned with Safe and Sustainable by Design SSbD guidelines. The proposal addresses the four stages of the NM lifecycle - synthesis, incorporation, use, and end-of-life, and considers five key dimensions: safety, environmental, economic, social, and functional.

To achieve this, the project employs standardized evaluation methodologies, including impact categories specific to nanotoxicity and eco-nanotoxicity, as well as a Multi-Objective Optimization Design (MOOD) algorithm to identify solutions that meet multiple performance indicators. A digital platform will support scientists, engineers, and policymakers in decision-making, reducing development time and costs, promoting transparency, and facilitating the sustainable industrial adoption of nanotechnologies.

Additionally, INTEGRANO will be compatible with other SSbD frameworks, enabling data exchange and the integration of results into different assessment metrics.